Alcohols and polyols
- (1)
- (55)
- (347)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
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- (28)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (116)
- (8)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
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- (2)
- (1)
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- (1)
- (2)
- (2)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
- (1)
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- (11)
- (1)
- (2)
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- (20)
- (21)
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- (3)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
- (2)
- (1)
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- (12)
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- (1)
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- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
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- (4)
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- (1)
- (1)
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- (6)
- (1)
- (1)
- (1)
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- (1)
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- (1)
- (1)
- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (82)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
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- (1)
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- (16)
- (1)
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- (2)
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- (1)
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- (1)
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- (279)
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- (1)
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- (280)
- (28)
- (2)
- (25)
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- (1)
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- (16)
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- (1)
- (8)
- (2)
- (733)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 5 MG
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker, useful for research into hypertension and glaucoma. It acts as a cardioselective beta-adrenergic receptor blocking agent, potentially safer for patients with reactive airway disease due to reduced systemic beta 2- and beta 1-adrenergic receptor blockade compared to other agents. In vivo studies show it can attenuate anxiety-like behavior during early withdrawal from chronic cocaine administration in rats.
- Selective beta1 adrenergic receptor blocker
- Used for research of hypertension and glaucoma
- Cardioselective beta-adrenergic receptor blocking agent
- Attenuates anxiety-like behavior during cocaine withdrawal in rats
- Potentially safer for patients with reactive airway disease
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | 98.1% | 457.91 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Topotecan hydrochloride is a Topoisomerase I inhibitor with potent antineoplastic activities, intended for research use only.
- Inhibits Topoisomerase I
- Displays potent antineoplastic activities
- Inhibits proliferation of human glioma cells and glioma stem cells
- Induces cell cycle arrest in G0/G1 and S phases
- Promotes apoptosis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG
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Trazodone hydrochloride is a triazolopyridine derivative classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. The compound exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits anti-depressant and anti-insomnious activities
- Antagonizes α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
- Binds to 5-HT1A receptor
- Reduces expression of neuroinflammatory markers
- Increases mRNA expression of BDNF and CREB
- Demonstrates neuroprotective effects
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Medchemexpress LLC 2-Pyridinecarboxylic acid, 3-mercapto-, hydrochloride (1:1) | 320386-54-7 | 96.4% | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It functions as a potent hypoglycemic agent by inhibiting glucose synthesis, and also inhibits Asn metabolism, leading to an increase in amino acids and amides.
- Orally active PEPCK inhibitor (Ki: 2-9 μM)
- Potent hypoglycemic agent
- Inhibits glucose synthesis
- Inhibits Asn metabolism
- Increases amino acids and amides
- Inhibits C2C12 cell proliferation in vitro
- Induces myogenic differentiation of C2C12 cells
- Reduces mRNA expression of Pck2 and genes associated with serine biosynthesis
- Reduces blood glucose in starved rats in vivo
- Neutralizes Salbutamol-mediated hyperglycemia in rabbits
- Reduces Pyruvate-induced blood glucose level in rats
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Medchemexpress LLC Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino] butyl ester, hydrochloride | 24735-18-0 | 347.79 | 1 ML
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Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino] butyl ester, hydrochloride | 24735-18-0 | 347.79 | 1 ML
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Medchemexpress LLC Imeglimin hydrochloride | 775351-61-6 | MFCD28167741 | 100.0% | 191.66 g/mol | C6H14ClN5 | 10 MG
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Imeglimin hydrochloride is the hydrochloride salt of imeglimin, an oral glucose-lowering small molecule that modulates mitochondrial metabolism and improves insulin sensitivity. It is supplied as a research-grade reagent for in vitro and in vivo studies of glucose homeostasis and mitochondrial function.
- High purity suitable for research applications.
- Molecular weight 191.66 g/mol and chemical formula C6H14ClN5.
- Provided as a solid in a 10 MG pack.
- Used to study insulin sensitivity and mitochondrial metabolism.
- Includes a product datasheet with analytical information.
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Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.27% | 274.79 | 25 MG
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PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.
- Binds to the surface cavity and stabilizes Y220C (a p53 mutant)
- Kd of 167 μM (p53-Y220C)
- Relative binding affinity (Kd) of 150 μM in Ln229 cells
- Slows down its thermal denaturation rate
- Reduces the cell viability of engineered variants of Ln229 cells (125 μM, 48 hours)
- Enhances pro-apoptotic activity in all variants of Ln229 cells (p53wt, p53Y220C, p53G245S, p53R282W) when combined with NSC 123127 (1 μM)
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Medchemexpress LLC Asenapine hydrochloride | 1412458-61-7 | 99.95% | 322.23 | 100 MG
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Asenapine hydrochloride is an atypical antipsychotic that acts as an antagonist of serotonin, adreno, dopamine, and histamine receptors. It is utilized in research for schizophrenia and bipolar disorder.
- Acts as an antagonist of serotonin receptors (pKi: 8.4-10.5).
- Acts as an antagonist of adrenoceptors (pKi: 8.9-9.5).
- Acts as an antagonist of dopamine receptors (pKi: 8.9-9.4).
- Acts as an antagonist of histamine receptors (pKi: 8.2-9.0).
- Purity of 99.95%.
- Soluble in H2O (100 mg/mL) and DMSO (50 mg/mL).
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | 99.8% | 1 ML
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Amiloride hydrochloride is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). It also acts as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is suitable for research applications targeting these pathways.
- Inhibitor of epithelial sodium channel (ENaC)
- Inhibitor of urokinase-type plasminogen activator receptor (uTPA)
- Blocker of polycystin-2 (PC2; TRPP2) channel
- Relatively selective ENaC inhibitor with IC50 ranging from 0.1 to 0.5 μM
- Demonstrated to reverse initial increases in collagen deposition in DOCA-salt hypertensive rats
- Delays the onset of proteinuria in stroke-prone spontaneously hypertensive rats (SHRSP)
- Antagonizes or prevents aldosterone actions in animal models of salt-dependent hypertension
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 100 MG
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SB-408124 Hydrochloride is a selective, non-peptide orexin receptor 1 (OX1) antagonist. It demonstrates high potency with Ki values of 57 nM in whole cells and 27 nM in membranes, exhibiting 50-fold selectivity over the OX2 receptor. This compound is for research use only.
- Potent OX1 receptor antagonist (Ki: 57 nM in whole cells, 27 nM in membranes)
- Exhibits 50-fold selectivity over OX2 receptor
- Attenuates orexin A-induced AVP mRNA levels in neuronal cultures
- Reduces anxiety and restores corticoliberin levels in vivo
- Demonstrates an anxiolytic effect
- Reduces mean arterial pressure in salt-sensitive rats
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Medchemexpress LLC BMT-090605 (hydrochloride) | 2231664-45-0 | 98.8% | 400.90 g/mol | C21H25ClN4O2 | 10 MG
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BMT-090605 hydrochloride is a research-grade small-molecule hydrochloride salt that functions as a potent inhibitor of adaptor protein-2 associated kinase 1 (AAK1), with reported activity against BIKE and GAK. It is supplied as a solid for use in in vitro kinase assays and preclinical pharmacology studies.
- Potent AAK1 inhibitor with low-nanomolar activity.
- Also inhibits BIKE and GAK, supporting broad kinase profiling.
- High purity (≈98.8%) suitable for research applications.
- Supplied as a solid light yellow powder for convenient handling.
- Stable when stored at -20°C as a powder for long-term storage.
- Packaged in small milligram quantities for laboratory use.
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Medchemexpress LLC Aptiganel hydrochloride | 137160-11-3 | 99.9% | 339.86 | 10 MG
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Aptiganel hydrochloride is a non-competitive NMDA receptor antagonist with neuroprotective effects. It is supplied as a solid, off-white to light yellow compound primarily for research purposes.
- Targets iGluR and NMDA receptor
- Involved in membrane transporter/ion channel and neuronal signaling pathways
- Powder stable for 3 years at -20°C or 2 years at 4°C
- Solution stable for 6 months at -80°C or 1 month at -20°C
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Medchemexpress LLC Amxi-5001 hydrochloride | 00-00-0 | 98.1% | 493.92 g/mol | C25H21ClFNO3 | 5 MG
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AMXI-5001 hydrochloride is a research-use small-molecule hydrochloride salt with dual PARP1/2 inhibitory activity and microtubule polymerization inhibition. It is intended for preclinical biochemical and cellular studies and is supplied with analytical specifications.
- Dual PARP1/2 and microtubule polymerization inhibitory activity.
- Suitable for in vitro and in vivo preclinical research.
- Hydrochloride salt form improves solubility for formulation.
- Soluble in DMSO at high concentration (≈100 mg/mL) for stock solutions.
- Solid storage recommended at 4°C; solutions stable at -80°C for extended storage.
- High chemical purity reported (~98%).
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Medchemexpress LLC SB-408124 hydrochloride | 1431697-90-3 | 98.8% | 392.83 g/mol | C19H19ClF2N4O | 10 MG
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SB-408124 hydrochloride is a selective, non-peptide antagonist of the orexin receptor 1 (OX1) used as a research reagent in orexin receptor pharmacology. It binds OX1 with nanomolar affinity and shows approximately 50-fold selectivity over OX2.
- High purity: 98.8%.
- Molecular weight: 392.83 g/mol.
- Chemical formula: C19H19ClF2N4O.
- Target activity: OX1 receptor antagonist; Ki = 57 nM (whole cell), 27 nM (membrane).
- Solubility: H2O 1 mg/mL (requires warming/ultrasonic); DMSO <1 mg/mL.
- Appearance: solid, white to gray.
- Recommended storage: sealed, away from moisture; in solvent -80°C for long-term storage.
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Medchemexpress LLC Sevelamer (hydrochloride) | 152751-57-0 | 98.0% | 186.08 (monomer) | 1 G
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Sevelamer (hydrochloride) is an orally active phosphate binding agent primarily used for research into hyperphosphatemia associated with chronic kidney disease. This substance consists of polyallylamine crosslinked with epichlorohydrin. It has a molecular weight of 186.08 (monomer) and is stable under recommended storage conditions, appearing as a white to off-white solid. It is classified as harmful to aquatic life with long lasting effects.
- Orally active phosphate binding agent
- Used for research of hyperphosphatemia with chronic kidney disease
- Decreases serum levels of gut-derived uremic toxins
- Reduces serum phosphate levels
- Stable under recommended storage conditions
- Solid appearance
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